MISSION

Based in Jumet, you will join a collaborative team full of passionate change-makers. 

As DSP Scientist (part of the development and production department), you will be responsible for the successful development of efficient purification processes, their scale-up and implementation for production of clinical material for viral vectors and other modalities. You will be one of our key specialists in developing purification processes for gene therapies, vaccines, and other modalities. You will be the one to select and implement the most efficient technologies to answer the objectives of our Customers and will work with all contemporary purification unit operations, including various types of filtration (depth filtration, TFF, normal flow filtration) and liquid chromatography (in multiple modalities). Working within a project team, you will collaborate closely with peers in process and analytical development, project management, process leads, and, of course, Exothera’s Clients. You will have an exciting opportunity to oversee purification development and implementation through the entire lifecycle of the project.

RESPONSIBILITIES

• Lead the design and execution of efficient, innovative downstream processes that meet the needs of our Clients for viral vectors and other modalities, 
• Propose and implement creative technical solutions to meet the project’s goals,
• Develop detailed experimental designs to facilitate the project process,
• Assume end-to-end responsibility for the execution of experimental plans with process technicians and lead related data interpretation,
• Plan purification operations and supervise them for your project as required, including communication with adjacent teams,
• Align and follow-up with process leads and project managers on the project baselines, risks, and other elements of project delivery.
• Prepare works reports, present results to the Customers, prepare internal operational documentation as required through the entire lifecycle of the project,
• Apply quality system as required and facilitate its continuous improvement,
• Promote and enforce (bio)-safety practices in the operational premises,

REQUIREMENTS & QUALIFICATIONS

• Master's Degree or higher with a minimum of 7 years of purification development and scale-up experience. Experience with adenovirus, adeno-associated virus, lentivirus, or MVA is a strong asset.
• Customer centricity mindset and motivation to work in a service environment, as Exothera is a CDMO.
• Good overall understanding of the process development and CMC beyond the purification domain.
• Strong understanding of compliance and cGMP considerations, ability to work efficiently in both R&D and GMP environments when needed.
• Leadership attitude and motivation to make a difference.
• Communication and organizational skills. General planning and project management skills are an asset.
• Fluent English is mandatory.

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