Here, in Nivelles (Belgium), you will join a collaborative team full of passionate change-makers. You will an actor of the successful development of a smart and innovative RNA vaccine production process. You will participate to the implementation of the process steps to generate crude and purified RNA bulk vaccine.In the team you will participate to USP, DSP and analytical activities linked to the development of the Drug Substance production process.

RESPONSIBILITIES

  • Execution of all operations associated with RNA vaccine production process development including : 
    • Preparation and filtration of buffers.
    • Chemical RNA synthesis.
    • Purification of RNA crude bulk.
    • Basic analytics (Agarose gel electrophoresis, absorbance 260 nm).
  • Management of lab and equipment used for operational work.
  • Monitoring and management of stocks of consumables and reagents specific to the project.
  • Maintenance of a clean and safe working area by following established housekeeping and safety routines
  • Writing and management of documentation related to experiments.
  • Data and results collection and record in defined forms with accuracy.
  • Results analysis and experimental report writing.
  • Adherence to standard operating procedures in all the operational tasks executed.
  • Correct use and implementation of quality management system within the field of activities (procedures/checklist/working instructions, etc.).
  • Identification and reporting of deviations from standard operating procedures and of unexpected events through initiation of related investigations.
  • Support of corrective and preventive actions related to deviations and unexpected events.
  • Contribution to general lab activities (housekeeping and maintenance).
  • Generation of process quality documentation (procedures, work instructions, templates, etc.).

REQUIREMENTS AND QUALIFICATIONS

  • Bachelor’s degree in Biology, Biochemistry or Biomedical Sciences
  • Minimum 2 years of experience in Molecular Biology.  
  • Experience in RNA synthesis is plus.
  • Integrity and transparency.
  • Strong sense of observation, inventive & critical mindset, scientific curiosity and problem-solving skills.
  • Proactivity, flexibility, work organizational skills.
  • Enthusiasm and agility to work on a variety of projects.
  • Capability to leverage know-how in order to participate in the development of the new generation solutions.
  • Capability to work in a cross-functional and multi-cultural team
  • Fluent in English (written and spoken)