A technology evolution
Univercells Technologies is introducing the new generation of the NevoLine biomanufacturing product family, the NevoLine Upstream platform.
This high-performance, low-footprint upstream manufacturing platform is suitable for multiple viral applications to support the booming gene therapy market and offer a cost-effective tool for rapid response to emerging infectious diseases. The innovative design aims to revolutionize upstream processing by intensifying and chaining all unit operations from inoculation to midstream processing to deliver a concentrated, clarified bulk.
With the NevoLine Upstream platform, commercial scale upstream production is possible in a 3 m² module, a 3-fold reduction in equipment footprint compared to conventional technologies.
Developed by virus production experts
The NevoLine Upstream platform was designed by virus manufacturing experts to address the needs of gene therapy and vaccine innovators and CDMOs for robust and cost-effective upstream viral vectors manufacturing. The new generation platform builds on the successful proof of concept with the first NevoLine which was specially designed for affordable production of a trivalent Sabin Inactivated Polio Vaccine (sIPV).
In application, the NevoLine sIPV platform demonstrated how the chaining of unit operations could intensify processes for drastic footprint and cost reductions, with the ability to deliver over 500,000 doses per batch below 0.30 EUR/dose, within a 10 m² equipment footprint.